loxP-cre system based in vivo recombination
10.3760/ema.j.issn.1006-9801.2012.02.023
- VernacularTitle:基于loxP-cre系统的细胞内重组技术
- Author:
Yonggang Lü
;
Haijun ZHU
- Publication Type:Journal Article
- Keywords:
Antibodies;
Phages;
In vivo recombination
- From:
Cancer Research and Clinic
2012;24(2):131-133
- CountryChina
- Language:Chinese
-
Abstract:
Phage display technology is improved in recent years.LoxP-cre system based in vivo recombination is the most important one. From double recombination system to single recombination system,from large scale sample sequencing to visual judgement, in vivo recombination makes it feasible to construct large natural antibody library, and it is favorable to get high affinity antibody. This review introduces the important improvement of in vivo recombination system.
