Clinical analysis of arrhythmia in chronic kidney disease patients without renal replacement therapy
10.3760/cma.j.issn.1001-7097.2012.02.005
- VernacularTitle:非透析慢性肾脏病患者心律失常的临床研究
- Author:
Haiying ZHANG
;
Qin XUE
;
Niansong WANG
;
Weiguo HU
;
Qing LI
;
Guihua JIAN
;
Xuping GAO
;
Haibing CHEN
;
Weiping JIA
- Publication Type:Journal Article
- Keywords:
Kidney disease;
Arrhythmia;
Diabetes;
Hypertension;
Ventricular hypertrophy;
Dynamic electrocardigram
- From:
Chinese Journal of Nephrology
2012;28(2):106-110
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the occurrence and risk factors of arrhythmia in chronic kidney disease (CKD) patients in different stages of renal function. Methods A total of 405 CKD patients were enrolled in this study and none of them received renal replacement therapy.The 24 h dynamic electrocardiogram (DCG) was performed,and baseline characteristics were compared.Multivariable Logistic regression analysis was used to examine the relationship between the severe arrhythmia and the potential risk factors,such as age,gender,CKD stage,diabetes,hypertension,hyperpotassaemia,left ventricular hypertrophy (LVH),etc. Results There were 69 patients (17.04％),79 patients (19.51％),82 patients (20.25％),88 patients (21.73 ％) and 87 patients (21.48％) in CKD stage 1,2,3,4 and 5,respectively.As high as 45.68％ of all the patients had severe arrhythmia,represented by 27.54％,29.11％,42.68％,57.95％ and 65.52％ in CKD stages 1-5 respectively.The occurrence of severe arrhythmia increased as the eGFR decreased in CKD stages 2,3,4 (p＜0.05).On multivariable Logistic regression analysis,the occurrence of severe arrhythmia was related to LVH,CKD stage,diaberes hyertension and hyperpotassaemia are signidicantly assoxiated with severe arrhythmia.
