Urgent need of establishment of new animal models of retinopathy of prematurity
10.3760/cma.j.issn.1005-1015.2012.01.003
- VernacularTitle:亟待新型早产儿视网膜病变动物模型的问世
- Author:
Yusheng WANG
;
Zhaojie CHU
- Publication Type:Journal Article
- Keywords:
Retinopathy of prematurity;
Disease Models,animal;
Editorial
- From:
Chinese Journal of Ocular Fundus Diseases
2012;28(1):8-10
- CountryChina
- Language:Chinese
-
Abstract:
The etiological factors and pathogenesis of retinopathy of prematurity (ROP) are still unclear,which restricted its effective prevention and treatment.The current animal model widely used in ROP investigation is oxygen-induced retinopathy model,which is lack of specificity,and does not mimic the real pathogenesis status of human ROP patients.Thus,we should refresh our concept,seek breakthroughs in multi-disciplines,integrate more risk factors of ROP,utilize the rising technique in transgenic animal,and improve the evaluation system for improving the current models or explore new animal models of ROP.It is important for prevention and treatment of ROP.
