Research progress in the multiple signaling transduction pathways of vitamin E succinate inducing apoptosis in breast cancer cells
10.3760/cma.j.issn.1006-9801.2012.01.025
- VernacularTitle:多种信号转导通路在维生素E琥珀酸酯诱导乳腺癌细胞凋亡中的研究进展
- Author:
Jiameng ZHANG
;
Li LI
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Signal transduction;
Apoptosis
- From:
Cancer Research and Clinic
2012;24(1):69-71
- CountryChina
- Language:Chinese
-
Abstract:
Vitamin E succinate (VES) has been recently recognized as a neotype tumor suppressor.However, the molecular mechanisms that VES induces apoptosis in breast cancer cells have not been validated. Current studies have indicated that VES induces breast cancer cell apoptosis through TGF-β signaling transduction pathways, Fas signaling transduction pathways, and JNK signaling transduction pathways.Other signaling transduction pathways still need to be investigated further.
