Pheochromocytoma in Children.
- Author:
Tae Sue HA
;
Jae Hong PARK
;
Il Soo HA
;
Hae Il CHEONG
;
Yong CHOI
;
Hyung Ro MOON
;
Gui Won PARK
- Publication Type:Original Article
- MeSH:
3-Iodobenzylguanidine;
Adrenergic Antagonists;
Calcium Channel Blockers;
Chest Pain;
Child*;
Diagnosis;
Female;
Headache;
Heart Murmurs;
Humans;
Hypertension;
Hypertensive Retinopathy;
Lethargy;
Male;
Pheochromocytoma*;
Retrospective Studies;
Sweat;
Sweating
- From:Journal of the Korean Pediatric Society
1994;37(7):961-968
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We Reviewed 10 hypertensive children with pheochromocytoma retrospectively and the following results were obtained. 1) Out of 10 patients, 7 were male and 3 female. Age ranged from 5.5 years to 13.8 years and their median age was 9.9 years. 2) They complained of sweating, lethargy, headache. or chest pain and so on. Hypertension were noticed in all patients. Heart murmurs were detected in 7 patients and hypertensive retinopathy in 70%. 3) The three cases arised at extraadrenal gland and bilaterality was seen in 3 patients. In the view of diagnosis, abdominal sonography, computerized tomography and urine VMA test revealed the sensitivity of 100%. But MIBG scan showed 60% in sensitivity. 4) Waiting for operation, their hypertension were controlled by adrenergic blockers or calcium channel blockers. They received tumorectomy successfully except one who was in hypertensive state after operation and followed up through OPD. In conclusion high suspicion for the existence of pheochromocytoma from the clinical manifestations should be entertained in any pediatric patients and biochemical and imaging studies were mandatory. Furthermore, for the accurate localization of tumors, several imaging studies should be collaborated.