Research progress on chemotherapy for brain metastasis of lung cancer
10.3760/cma.j.issn.1006-9801.2012.01.024
- VernacularTitle:肺癌脑转移的化疗研究进展
- Author:
Min WEI
- Publication Type:Journal Article
- Keywords:
Lung neoplasms;
Drug therapy,combination;
Blood-brain barrier;
Neoplasm metastasis
- From:
Cancer Research and Clinic
2012;24(1):67-69
- CountryChina
- Language:Chinese
-
Abstract:
Brain metastases from lung cancer is a significant cause of morbidity and mortality,whichis lack of effective treatment.Because chemotherapeutic drugs are thought to not cross the blood-brain barrier(BBB), the role of chemotherapy in the treatment of brain metastases remains controversial. For yearsradiotherapy has been the standard treatment for brain metastases.However, recent studies have confirmedthat the BBB in patients with brain metastases tumors are broken down.At the same time,researchers havefound some new methods for chemotherapeutic drugs to reach the brain metastases.Chemotherapy will play amore and more active role in the treatment of brain metastases tumors.
