The Prevalence and Genetic Pattern of Clinodactyly in Korean Populations.
10.11637/kjpa.2016.29.3.99
- Author:
Duhyun SONG
1
;
Junhyuk CHUNG
;
Hye Gyeong SHIN
;
Soo Jung JUNG
;
Jae Ho LEE
Author Information
1. Medical course, Yonsei University College of Medicine, Korea.
- Publication Type:Original Article
- Keywords:
Clinodactyly;
Autosomal dominant;
Hand deformity;
Smartphone pinky
- MeSH:
Female;
Hand Deformities;
Humans;
Inheritance Patterns;
Male;
Prevalence*;
Wills
- From:Korean Journal of Physical Anthropology
2016;29(3):99-103
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Clinodactyly, as rare congenital malformation, refers to a curvature of a digit in a radial or ulnar direction in the coronal plane. The abnormality is inherited as an autosomal dominant trait. And its frequency was low, however, it was higher by accompanying other congenital anomaly. In present study, the frequency and genetic characteristics of clinodactyly were investigated. In 100 family (382 peoples), clinodactyly was found in 4.7% (n=18). All clinodactyly were bilateral and it was more frequent in female (6.8%) than male (2.6%), without statistical difference (p=0.056). Its inheritance was autosomal dominant trait in 80% (4/5) families, however, one family did not have any inheritance pattern. We described the frequency and clinical implication of clinodactyly, and this description will be lead to an improved understanding of its spectrum and inheritance.
