Activity of attentional and executive cortex and its relationship with cognitive impairment in subcortical ischemic vascular dementia
10.3760/cma.j.issn.1006-7876.2012.01.007
- VernacularTitle:皮质下血管性痴呆患者脑注意和执行功能区激活特征及与认知功能损害的相关性
- Author:
Chuanming LI
;
Jian WANG
;
Lin CHENG
;
Jian ZHENG
- Publication Type:Journal Article
- Keywords:
Dementia,vascular;
Cognition disorders;
Magnetic resonance imaging
- From:
Chinese Journal of Neurology
2012;45(1):24-26
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the activity of attentional and executive cortex and its relationship with cognitive impairment in subcortical ischemic vascular dementia (SIVD).MethodsTwenty patients with SIVD and twenty normal control subjects who were matched by age,sex and education were enrolled.All of them underwent fMRI using SEMENTS 3.0T MR during Stroop task performance. The correlation between cognitive impairment and cortex activation in fMRI was analyzed.Results Cortical activation of bilateral dorsolateral prefrontal cortex,Nentrolateral prefrontal cortex,inferior parietal lobe have closed correlation with total score,visual trabecular spaces and execution,attention,verbalization,delayed memory and orientation score in MoCA test ( r =0.447-0.837,P ＜ 0.05 ).ConclusionsCortex activation in fMRI can reflex the cognitive impairment of SIVD.
