Differentiation of stroke subtype classification by ASCO and modified TOAST
10.3760/cma.j.issn.1006-7876.2012.01.009
- VernacularTitle:ASCO与改良TOAST病因分型对缺血性卒中病因诊断的比较
- Author:
Wanyu SHANG
;
Junyan LIU
- Publication Type:Journal Article
- Keywords:
Brain ischemia;
Stroke;
Atherosclerosis;
Thrombosis
- From:
Chinese Journal of Neurology
2012;45(1):32-35
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo compare the differences in stroke subtype classification between ASCO and modified TOAST.MethodsAll 425 first-ever ischemic stroke patients were recruited and classified into different stroke subtypes according to the ASCO and modified TOAST criteria.Results Comparing ASCO grade 1 with modified TOAST,more patients were classified as atherosclerosis (60.2％ vs 57.9％ ; x2 =2.68,P=0.132) and fewer as small artery disease and cardiac disease subtype (13.4％ vs 14.8％ and 8.5％ vs 8.7％ ; x2 =1.30 and 0.00,P =0.238 and 1.000,respectively).ASCO grade 1 did not reduce the proportion of cause undetermined patients compared with modified TOAST ( 15.5％ vs 16.2％ ; x2 =0.09,P =0.795 ). Agreement was showed in every subtype categories between the two approaches.Agreement for atherosclerotic cause and small artery disease was very good ( all κ over 0.81 ),and for the cardiac disease subtype was good (κ: 0.61-0.80). Conclusion Agreement can be found in every subtype categories between ASCO and modified TOAST classification.ASCO grade 1 does not reduce the proportion of cause undetermined cases compared with modified TOAST,but the subtype categories characteristics of the two approaches should be considered in practice.
