The influence of ginkgo dipyridolum injection on blood-rheological and coagulation function in pationts with AECOPD
10.3760/cma.j.issn.1673-4246.2012.09.008
- VernacularTitle:银杏达莫注射液对慢性阻塞性肺疾病急性发作期患者血液流变学及凝血功能的影响
- Author:
Wanning TONG
;
Zhiyu ZHAO
;
Anshan ZHUO
;
Yushu CAO
- Publication Type:Journal Article
- Keywords:
Ginkgo dipyridolum injection;
Blood-rheological;
Coagulation function;
Chronic obstructive Pulmonary disease with acute exacerbation
- From:
International Journal of Traditional Chinese Medicine
2012;34(9):791-793
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo evaluate the influence of ginkgo dipyridolum injection on blood-rheological and coagulation function in pationts with AECOPD.Methods78 cases of patients with AECOPD were divided into group A (38 cases)and group B (40 cases)by mean of digital random table method.The routine treatment including oxygen inhalation,spasmolytics and anti-infection was given to patients in both groups while ginkgo dipyridolum injection (30 ml/d)was additionally added to patients in group B for two weeks.The blood-rheological and coagulation function were evaluated.ResultsAs for blood-rheological after the treatment,whole blood high shearing viscosity(5.25 ± 1.24)mPa · S,low shearing viscosity (11.12 ±2.43) mPa · S,plasma viscosity (2.06± 0.14 ) mPa · S and hematocrit (45.52 ± 2.78) ％ in the group A indicated significant differences compared to those in group B [ (4.83 ± 1.42)mPa· S,(8.78± 3.02) mPa · S,(1.73 ±0.21) mPa · S,(39.05 ± 3.41) ％],(P＜0.05); as for coagulation function after the treatment,PT (13.14± 1.31 ) S,APTT (30.85±5.24)S,FIB (4.99±1.04)S,D-D (1.42±0.23)mg/L in the group A indicated significant differences compared to those in group B [ (14.78 ± 3.13) S,(36.67 ± 8.12)S,(3.81 ± 0.42) S,(0.84 ±0.39) mg/L],(P＜0.05).ConclusionFor the patients with AECOPD,the ginkgo dipyridolum injection can decrease hood-viscosity,and obviously improve hypercoagulabale state.
