Study the feasibility of kilovolt cone beam CT organs at risk contouring automatically using deformation registration in the radiotherapy of lung
10.3760/cma.j.issn.1004-4221.2012.05.019
- VernacularTitle:肺癌锥形束CT与计划CT形变配准自动勾画危及器官可行性研究
- Author:
Yong HOU
;
Yong YIN
;
Changsheng MA
;
Guanzhong GONG
- Publication Type:Journal Article
- Keywords:
Tomography,X-ray computed;
Tomography,X-ray computed,cone beam;
Image registration;
Delineating organs at risk
- From:
Chinese Journal of Radiation Oncology
2012;21(5):460-463
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo quantitative analysis the difference of organ contour using planning CT and kilovolt cone beam CT (KVCBCT) deformable registration.MethodsOne set planning CT image and ten sets of KVCBCT image of one patient were choose and total five patients.Organ contour were automatic outlined to using deformable registration.To compare the organ contours different of deformable registration (DR) and rigid registration (RR).Statistic analysis was executed with paired t-test for dice similarity coefficient (DSC) value and sensitiveness (SENS) value.ResultsThe DSC value of body,left,right lung,heart and spinal respectively:0.971 and 0.980 ( t =3.89,P =0.000 ),0.836 and 0.873 ( t =4.41,P =0.000),0.873 and 0.888 ( t =3.88,P =0.000 ),0.738 and 0.764 ( t =4.83,P =0.000 ),0.666 and 0.677 ( t =2.04,P =0.047 ).The SENS value:0.975 and 0.981 ( t =1.41,P =0.003 ),0.914 and 0.803(t=-6.88,P=0.000),0.926 and 0.800(t=-7.06,P=0.045),0.782 and 0.708(t=-2.50,P=0.040),0.625 and 0.796 (t =-9.09,P =0.000).ConclusionsRR is at a competitive disadvantage in terms of organ contour outline.The body,left and right lung that are used DR have advantage over the heart and spinal.
