The correlation between the carotid atherosclerosis unstable plaque, lipoprotein (a) levels with acute cerebral infarction patients

VernacularTitle:颈动脉粥样硬化不稳定斑块、脂蛋白(a)水平与急性脑梗死的相关性
Author: Wenzhen LUO ; Yingxin LU ; Rongqiang SHI
Publication Type:Journal Article
Keywords: Carotid atherosclerosis; Unnstable plaque; Lipoprotein ( a ); Cerebral infarction
From: Chinese Journal of Primary Medicine and Pharmacy 2012;19(17):2601-2603
CountryChina
Language:Chinese
Abstract: Objective To explore the correlation between the carotid atherosclerosis unstable plaque lipoprotein(a) [ Lp(a)]levels with acute cerebral infarction patients.Methods 120 patients with acute cerebral infarction were selected as the research group,and at the same period,120 health cases were selected as the control group.The level of Lp(a) of the two groups was tested,and neck vascular color dopplar ultrasound examination was conducted.Results The incidence of atherosclerotic plaque in carotid artery and unstable plaques was 70.8％,51.7％,respectively,and significantly higher than that of the control group(25.8％,6- 7％ ) ( x2 =5.12,6.43,all P ＜0.05 ).The Lp(a) level of the research group[ (273.6 ± 221.7 )ag/L] was significantly higher than that of the control group[ ( 81.6 ± 64.9) mg/L ] ( t =6.53,P ＜ 0.05 ).Conclusion High level of LP(a) is the independent risk factor of cerebral infarction.The instability of carotid atherosclerotic plaques is the important cause of cerebral infarction.