The influence of edaravone on cognitive ability in patients with vascular dementia

VernacularTitle:依达拉奉对血管性痴呆患者认知功能的影响
Author: Heqi ZHANG
Publication Type:Journal Article
Keywords: Dementia,vascular; Cognition disorders; Edaravone injection; Piracetam
From: Chinese Journal of Primary Medicine and Pharmacy 2012;19(18):2729-2730
CountryChina
Language:Chinese
Abstract: Objective To observe the influence of edaravone on the cognitive ability in patients with vascular dementia(VD).Methods 70 cases with mild to moderate VD were randomly divided into observation group( edaravone treatment) and control group( piracetarn treatment),35 cases in each group.Treatment cycle was two weeks.The scores of MMSE,CDT,MoCA were compared before and after treatment between the two groups.Results The scores were found to be significantly higher after use edaravone in the observation group ( t =4.21,1.45,12.37,all P ＜0.05 ).The score had no difference before and after treatment in the control group ( P ＞ 0.05 ).Conclusion Edaravone could improve cognitive abilitys in VD patients through its function of anti-oxidant and free-radical scavenging.