The clinical study on the relationship between blood uric acid and insulin resistance in the patients with gestational diabetes mellitus (GDM)
10.3760/cma.j.issn.1008-6706.2012.18.016
- VernacularTitle:妊娠期糖尿病患者血尿酸与胰岛素抵抗的关系
- Author:
Qian RONG
- Publication Type:Journal Article
- Keywords:
Diabetes,gestational;
Uric acid;
Insulin resistance
- From:
Chinese Journal of Primary Medicine and Pharmacy
2012;19(18):2750-2751
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between blood uric acid and insulin resistance in the patients with GDM.Methods The various biochemical parameters such as uric acid ( UA),fasting plasma glucose (FPG),fasting insulin(FINS) and insulin resistance index(IRI) were detected in 80 patients with GDM and 40 normal pregnant women.80 patients with GDM were divided into A group ( hyperuricemia,UA ＞ 360 μmol/L,31 cases ) and B group (normouricemia,49 cases ) to observe and compare the changes of each biochemical parameter.Results Compared to the control group,there were significant differences in FPG [ (7.87 ± 0.69 ) mmol/L,t =17.0842 ],UA [ ( 308.87 ± 79.12) μmol/L,t =2.1758 ],FINS [ ( 15.87 ± 5.12 ) mU/L,t =3.5410 ] and IRI [ (2.27 ±0.72),t =7.1247] (all P ＜0.05).There were significant differences in FPG(8.38 ± 0.46) mmol/L,TG ( 373.97 ± 29.12 ) μmol/L,FINS ( 15.87 ± 5.12 ) mU/L,IRI ( 2.47 ± 0.12 ) between group A and group B ( t =5.7187,12.3116,2.3185,11.2835,all P ＜ 0.05 ).The blood uric acid level was positively related to FINS,IRI,TG in the patients with GDM( r =0.839,0.720,0.660,all P ＜ 0.05 ).Conclusion There was correlation between the blood uric acid level and insulin resistance in the patients with GDM.
