Renal stenosis resulting from fibromuscular dysplasia and its surgical treatment: report of 16 cases
10.3760/cma.j.issn.1007-631X.2012.10.003
- VernacularTitle:肌纤维发育不良所致肾动脉狭窄16例的治疗
- Author:
Zhenyu SHI
;
Weiguo FU
;
Daqiao GUO
;
Bin CHEN
;
Xin XU
;
Junhao JIANG
;
Jue YANG
;
Ting ZHU
;
Zhihui DONG
;
Yun SHI
;
Lixin WANG
;
Xiao TANG
;
Yuqi WANG
- Publication Type:Journal Article
- Keywords:
Renal artery obstruction;
Angioplasty,balloon;
Hypertension,renal;
Fibromuscular dysplasia
- From:
Chinese Journal of General Surgery
2012;27(10):786-788
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical characteristics and surgical treatment of renal stenosis resulting from fibromuscular dysplasia ( FMD ). Methods 16 cases from 1998 to 2011 were reviewed,the average age was (28 ± 13 ) years old. Among them, all patients suffered refractory hypertension and only one presented renal dysfunction. Aorto-renal bypass was performed in 2 cases.Resection and reconstruction was performed in 2 cases,balloon angioplasty in 10 and stent implantation in 3.Results There was 1 death peri-operatively.13 out of 15 cases were followed-up with no death.Significant decline of blood pressure [ (134 ± 14 )/( 83 ± 8 ) mm Hg vs.( 151 ± 17 )/( 96 ± 16 ) mm H g ( P ＜ 0.01 ) ]and 100％ effective rate were observed.The creatine level were preserved after surgical treatment [ (61 ±22) μmol/L vs.(69 ± 22) μmol/L,(P ＞ 0.05 ) ] with 4 cases improved and the other 9 stable.12 patients received ultrasound surveillance with only one case of 20％ restenosis. Conclusions Renal stenosis due to FMD are most common in children and the youth with hypertension as major presentation. Balloon angioplasty is the first choice of surgical treatment with positive efficacy.
