Change and clinical significance of ischemia modified albumin in transient myocardial ischemia before and after radio frequency ablation
10.3760/cma.j.issn.1008-6315.2012.10.014
- VernacularTitle:缺血修饰白蛋白在射频消融术前后的变化及其临床意义
- Author:
Bo CUI
;
Yujie BAI
;
Wei YU
- Publication Type:Journal Article
- Keywords:
Radio frequency ablation;
Ischemia modified albumin;
Cardiac troponin T;
Creatine kinase MB;
Cardiac arrhythmia
- From:
Clinical Medicine of China
2012;28(10):1053-1055
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the changes and clinical significances of ischemia modified albumin (IMA),cardiac triponin T (cTnT) and creatine kinase MB (CK-MB) in transient myocardial ischemia induced by radio frequency ablation ( RFA ) in patients with arrhythmia.Methods One hundred and twelve patients with arrhythmia undergoing RFA and 91 patients undergoing CAG were evaluated with blood levels of IMA,cTnT and CK-MB before and 3 and 6 hours after operation.Results Serum levels of IMA at 3 h [ (80.62 ± 7.53 )U/ml ] and 6 h [ (76.37 ± 9.21 ) U/ml ] after operation rose significantly (P ＜ 0.05 ) in the 112 cases of RFA compared with the preoperative [ ( 45.42 ± 7.00 ) U/ml ].While the levels of IMA were not significantly different at 3 and 6 hours after CAG in the 91 patients compared with before sugery ( P ＞ 0.05).The levels of cTnT and CK-MB remained unchanged between the two groups after the procedures ( P ＞ 0.05 ).Conclusion The levels of IMA were quickly increased after myocardial ischemia induced by RFA and this change occurred earlier than that of cTnT.IMA is an early diagnostic biochemical marker of myocardial ischemia.
