The observation and analysis of the levels of perioperative serum alpha-fetoprotein and carcinoembryonic antigen in patients with primary liver cancer undertaken transcatheter arterial chemoembolization
10.3760/cma.j.issn.1673-4904.2012.26.011
- VernacularTitle:原发性肝癌行肝动脉化疗栓塞术围手术期血清甲胎蛋白、癌胚抗原水平的观察与分析
- Author:
Benzun WEI
;
Chao SHEN
;
Guangtao SUN
;
Ronghua QI
- Publication Type:Journal Article
- Keywords:
Liver neoplasms;
Embolization,therapeutic;
Carcinoembryonic antigen;
Alphafetoproteins
- From:
Chinese Journal of Postgraduates of Medicine
2012;35(26):32-34
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the change of perioperative serum alpha-fetoprotein (AFP) and carcinoembryonic antigen (CEA) in patients with primary liver cancer undertaken transcatbeter arterial chemoembolization (TACE).Methods One hundred and two patients with primary liver cancer were performed with TACE treatment.The levels of AFP and CEA after treatment 3 d,1 week,3 weeks were detected and compared.Results The levels of AFP after treatment 3 d and 1 week were higher than that before treatment,but there was no significant difference [(549 ±30),(530 ±30) μg/L vs. (527 ±40) μg/L] (P ＞ 0.05).After treatment 3 weeks,the levels of AFP significantly decreased than that before treatment [ (351 ± 20) μ g/L vs.(527 ± 40) μ g/L ] (P ＜ 0.05 ).The levels of CEA after treatment 3 d,1 week,3 weeks were significantly lower than that before treatment [(410 ± 15),(350 ± 20),(200 ± 10) μg/L vs.(570 ±22) μ g/L] (P ＜0.05).After treatment 3 weeks,the levels of AFP and CEA achieved normal.Conclusions TACE in treatment for primary liver cancer can achieve better therapeutic effect,significantly improve the symptoms,decrease the levels of AFP and CEA.To control the indication and contraindication,perform TACE in time can decrease mortality,improve prognosis,and is valuable in clinic.
