Fibrinogen is a predictor for progressive proteinuria in type 2 diabetes
10.3760/cma.j.issn.1000-6699.2012.09.008
- VernacularTitle:纤维蛋白原是2型糖尿病尿蛋白进展的预测指标
- Author:
Yiping YANG
;
Juhong YANG
;
Baocheng CHANG
;
Chunyan SHAN
;
Miaoyan ZHENG
;
Ying WANG
;
Huizhu REN
;
Liming CHEN
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type 2;
Diabetic nephropathies;
Coagulation;
Proteinuria;
Fibrinogen
- From:
Chinese Journal of Endocrinology and Metabolism
2012;28(9):726-728
- CountryChina
- Language:Chinese
-
Abstract:
The association of coagulation function with progressive proteinuria in type 2 diabetic patients was retrospectively analyzed.With increasing microalbuminuria,fibrinogen level was increased significantly.Fibrinogen was an independent risk factor of microalbuminuria. In patients as the early-stage diabetic nephropathy (DN)progressed to clinical-stage DN,the baseline level of fibrinogen was also increased [ ( 3.5 ± 0.9 vs 3.0 ± 0.6 ) g/L,P＜0.05 ].Fibrinogen may serve as a useful predictor of progressive proteinuria in type 2 diabetes.
