Study on the related risk factors with atherogenic index of plasma in male type 2 diabetic patients
10.3760/cma.j.issn.1000-6699.2012.09.006
- VernacularTitle:男性2型糖尿病患者血浆致动脉粥样硬化指数相关危险因素研究
- Author:
Xiaoming WU
;
Wei ZHAO
;
Jia LIU
;
Bixiao CHEN
;
Wei LI
;
Hong ZHANG
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type 2;
Atherogenic index of plasma;
Risk factors
- From:
Chinese Journal of Endocrinology and Metabolism
2012;28(9):720-722
- CountryChina
- Language:Chinese
-
Abstract:
133 male patients with type 2 diabetes mellitus were divided into non-atherogenic phenom( N group ) and atherogenic phenom( A group) according to the c utpoint of atherogenic index of plasma (AIP) at 0.06.The clinical chemistry data were compared between two groups.The results showed that body mass index ( BMI ),waist-tohip ratio (WHR),homeostasis model assessment insulin resistance index ( HOMA-IR ) and insulin secretion index (HOMA-IS),serum triglyceride (TG),very low density lipoprotein-cholesterol (VLDL-C),serum uric acid ( SUA ),urine uric acid ( UUA ),and urine micro-albumin ( UMA ) levels in A group were higher than those in N group ( all P＜0.05 ),while high density lipoprotein-cholesterol ( HDL-C ) level was lower ( P＜0.01 ),as well as higher coronary heart disease incidence in A group as compared with N group( P＜0.05 ).Correlation analysis revealed that AIP was positively related with age,BMI,WHR,HOMA-IR,HOMA-IS,systolic blood pressure,diastolic blood poressure,TG,total cholesterol,VLDL-C,SUA,UUA,and UMA( all P＜0.05 ),and negatively related with HDL-C (P＜0.01).Multivariant stepwise linear regression analysis revealed that TG,HDL-C,V LDL-C,and UUA were independent influential factors for AIP.
