The related factors analysis of hepatitis B liver cirrhosis patients with secondary glucose metabolism disorders
10.3760/cma.j.issn.1008-6706.2012.17.008
- VernacularTitle:乙型肝炎肝硬化患者继发糖代谢紊乱的相关因素分析
- Author:
Donglan ZHANG
;
Cuiling ZHENG
;
Shuxiang WANG
;
Zhigang ZHANG
- Publication Type:Journal Article
- Keywords:
Hepatitis B;
Liver cirrhosis;
Glucose metabolism;
Risk factor
- From:
Chinese Journal of Primary Medicine and Pharmacy
2012;19(17):2575-2576
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the related factors analysis of hepatitis B liver cirrhosis with secondary glucose metabolism disorders.Methods 184 patients with hepatitis B liver cirrhosis were selected as the research object and were given 75g oral glucose tolerance test( OGTI),then they were divided into three groups[ normal glucose tolerance(NGT) group,impaired glucose tolerance and impaired fasting glucose regulation impairment(IGR) group,diabetic( DM ) group ] according the results.The general information,laboratory examination and viral load of three groups were compared.Results ( 1 ) The difference of age,waist size,weight,body mass index data and hepatitis B virus load in IGR group and DM group compared with NGT group were statistically significant difference ( all P ＜0.05 ),IGR compared with DM group,all index comparative differences were not significant (all P ＞ 0.05 ).(2)As the aggravating of glucose metabolism disorder,the positive rate of HBsAg,HBeAg and former S1 antigen of NGT group,IGR group and DM group were gradually raised ( all P ＜ 0.05 ).Conclusion The body mass index and hepatitis B virus load are relatively independent risk factors of secondary glucose metabolism disorders in patients with hepatitis B liver cirrhosis,and which are positive correlation with it.However,gender,age,blood lipids are not obvious correlation with secondary glucose metabolism disorders.
