Application of high volume continuous blood purification in the treatment of multiple organ dysfunction syndrome

VernacularTitle:高容量连续性血液净化在多器官功能障碍综合征患者治疗中的应用
Author: Qichun ZHANG ; Xibin FANG ; Zhiye LI ; Weihong CHEN ; Xiaobin NI ; Suzhi CHEN ; Yang LUO ; Jiping CHEN
Publication Type:Journal Article
Keywords: Hemodiafiltration; Multiple organ failure
From: Chinese Journal of Primary Medicine and Pharmacy 2012;19(17):2598-2599
CountryChina
Language:Chinese
Abstract: Objective To compare the effect of high volume continuous blood purification (CBP) with routine CBP on multiple organ dysfunction syndrome(MODS).Methods 38 patients with MODS were randomly divided into high volume CBP group( treatment group,18 cases) and routine CBP group (control group,20 cases).And they were respectively detected on mean arterial pressure(MAP),dosage of Dopamine,PaO2/FiO2,APACHE [ score,lactic acid,length of stay and mortality in ICU post-treatment 24h and 48h.Results Compared with control group,MAP and PaO2/FiO2 on treatment group were more higher( P ＜ 0.05 ),while dosage of Dopamine,APACHE Ⅱ score,lactic acid were significantly shorter than these of treatment group( P ＜ 0.05 ),and length of stay and mortality in ICU were significantly lower than those of treatmen group [ ( 8.54 ± 4.15 ) d vs ( 11.82 ± 5.76) d,P ＜ 0.05:22.2％ vs 35.0％,P ＜0.05 ].Conclusion High volume CBP could reduce the mortality in ICU compared with control group routine CBP.