Clinical analysis of allergic bronchopulmonary aspergillosis: a report of 48 patients
10.3760/cma.j.issn.1671-7368.2012.09.022
- VernacularTitle:变态反应性支气管肺曲菌病48例临床分析
- Author:
Yiliang SU
;
Beilan GAO
;
Jinming LIU
;
Weijun CAO
;
Kebin CHENG
- Publication Type:Journal Article
- Keywords:
Hypersensitivity;
Aspergillosis,allergic bronchopulmonary
- From:
Chinese Journal of General Practitioners
2012;11(9):685-686
- CountryChina
- Language:Chinese
-
Abstract:
To retrospectively analyze the clinical data of 48 patients with allergic bronchopulmonary aspergillosis (ABPA) at Shanghai Pulmonary Hospital.There were 23 males and 25 females with a mean age of (36 ± 15) years.Their clinical manifestations included wheeze,cough,sputum production,sputum plugs,fever,hemoptysis,weight loss,chest pain,weakness and night sweats.They had a high peripheral blood eosinophilia,a higher serum total IgE,a higher level of aspergillosis fumigatus-specific IgE and positive immediate skin-prick test to aspergillus fumigatus.Aspergillus species were detected in sputum samples of 26 patients.Chest computed tomography (CT) was performed in 48 patients.There were patchy infiltrations (n =45),transient infiltrations (n =40),central bronchiectasis (n =35) and mucoid impaction (n =18).Obstructive ventilation dysfunction was confirmed by lung function test.
