Approach to the patient with primary hypothyroidism accompanied by pituitary hyperplasia and increased serum creatine kinase level
10.3760/cma.j.issn.1000-6699.2012.09.017
- VernacularTitle:伴肌酸激酶升高、垂体增大的原发性甲状腺功能减退症的临诊应对
- Author:
Fei GUO
;
Chenlin DAI
;
Tiehong ZHU
;
Mingcai QIU
- Publication Type:Journal Article
- Keywords:
Primary hypothyroidism;
Pituitary hyperplasia;
Creatine kinase;
Ultrastructural pathology
- From:
Chinese Journal of Endocrinology and Metabolism
2012;28(9):761-764
- CountryChina
- Language:Chinese
-
Abstract:
Pituitary hyperplasia may be found in patients with primary hypothyroidism as the decreased thyroid hormone level attenuates negative feedback effect.Sometimes the enlarged pituitary may be misdiagnosed as a pituitary tumor.Patients with long term untreated hypothyroidism often have extremely high level of serum creatine kinase and thus may be misdiagnosed as suffering from myositis.In order to increase the awareness of the nonspecific symptoms of primary hypothyroidism,this article introduces the diagnosis and treatment of a patient with primary hypothyroidism with raised serum creatine kinase level and pituitary hyperplasia.
