The influence of sealing tube with urokinase on the malfunction of central venous catheter with Dacron ring
10.3760/cma.j.issn.1008-6706.2012.19.010
- VernacularTitle:尿激酶封管对带涤纶环中心静脉留置导管功能不良的影响
- Author:
Liying CAO
;
Chunqing GAI
;
Yueming YU
;
Jing HAN
;
Yong ZHANG
- Publication Type:Journal Article
- Keywords:
Renal dialysis;
Central venous catheter;
Malfunction;
Urokinase
- From:
Chinese Journal of Primary Medicine and Pharmacy
2012;19(19):2898-2900
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of sealing tube with regular urokinase for the malfunction of central venous catheter(CVC) in patients with hemodialysis (HD).Methods This was a prospective randomized controlled study,132 HD patients with cuff CVC were studied.In the early stage,52 H D patients without 80 patients with regular catheter-locking solution of urokinase.To analyze effect of cuff CVC malfunction,blood flow(BF),dialysis adequacy,anemia and serum albumin (ALB) with regular catheter-locking solution of urokinase.The incidence of catheter malfunction was calculated based on the catheter dysfunction in the first 3 months.Clinical index was measured,recorded BF and calculated urea clearance rate (Kt/V).Results HD patients catheter-locking solution with regular urokinase could reduce the incidence of dialysis catheter malfunction ( 26.3％ vs 32.7％,x2 =32.727,P ＜0.01 ),increase the BF,Kt/V,levels of hemoglobin(HGB) and ALB(P＜0.05 or P ＜0.01).Conclusion Regular catheter-locking solution with urokinase is effective in reducing HD patients incidence of dialysis CVC malfunction,increasing patients BF,dialysis adequacy and the level of ALB,improving anemia.
