Study of the relationship between HBV serum markers and HBV-DNA level
10.3760/cma.j.issn.1008-6706.2012.16.019
- VernacularTitle:乙型肝炎患者血清标志物与HBV-DNA水平的关系探讨
- Author:
Xu WANG
;
Yongyong ZHANG
- Publication Type:Journal Article
- Keywords:
Hepatitis B;
Serum markers;
HBV-DNA
- From:
Chinese Journal of Primary Medicine and Pharmacy
2012;19(16):2435-2437
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the relationship between hepatitis B markers and HBV-DNA content.Methods230 cases with hepatitis were selected.ELISA method was used to detect serum markers,PCR method fordetecting the content of HBV-DNA.ResultsIn 76cases of HBeAg positive specimens,72 cases were HBV-DNA positive,the positive rate was 94.7％ ; in 154 patients with HBeAg negative specimens,72 cases were HBV-DNA posifive,the positive rate was 46.7％.The difference between HBeAg positive group and HBeAg negative group was statistically different( P ＜0.01 ).ConclusionIn patients with chronic hepatitis B,serum markers reflected,HBV can understand the in vivo infection,cannot directly reflect the in vivo replication of HBV.Detection of HBV-DNA content can better reflect the virus replication.
