Analysis of related risk factors of prognosis in patients with systemic lupus erythematosus complicated with lung infection

VernacularTitle:系统性红斑狼疮合并肺部感染患者预后的相关危险因素分析
Author: Shuqian DONG ; Peng ZHANG ; Weiguo JIANG
Publication Type:Journal Article
Keywords: Lupus erythematosus,systemic; Prognosis; Risk factors; Lung infection; Logistic regressive analysis
From: Chinese Journal of Postgraduates of Medicine 2012;35(19):28-29
CountryChina
Language:Chinese
Abstract: Objective To investigate the related risk factors of prognosis in patients with systemic lupus erythematosus (SLE) complicated with lung infection.Methods The clinical data of 84 cases with SLE complicated with lung infection were analyzed retrospectively.Multivariate Logistic regressive analysis was made with death and survival as the independent variable.Results There were 23 out of 84 patients dead,and fatality rate was 27.38％.Multivariate Logistic regressive analysis showed that the urine volume,immune globulin treatment,cyclophosphamide pulse therapy,plasma albumin and SLE disease activity (SLEDAI) score were the risk factors that influenced the prognosis (OR =0.53,0.72,4.29,0.94,1.58,respectively,P＜0.0l or ＜0.05).Conclusions The prognosis of patients with SLE complicated with lung infection is the result of the joint action of many factors.The higher SLEDAI score and cyclophosphamide pulse therapy are the independent risk factors of the prognosis.The increase of plasma albumin level and urine production and immune globulin treatment are helpful to decrease the fatality rate.