The effects of calcium dobesilate combined with irbesartan in treating early diabetic nephropathy
10.3760/cma.j.issn.1008-6706.2012.16.018
- VernacularTitle:羟苯磺酸钙联合厄贝沙坦治疗早期糖尿病肾病
- Author:
Mei PENG
;
Xiancong WANG
;
Kai LUO
;
Qinghua ZHENG
;
Huanlan WANG
- Publication Type:Journal Article
- Keywords:
Diabetic nephropathy;
Calcium dobesilate;
Irbesartan
- From:
Chinese Journal of Primary Medicine and Pharmacy
2012;19(16):2434-2435
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo observe the therapeutic effects of calcium dobesilate combined with irbesartan in treating early diabetic nephropathy ( DN ).Methods65 patients with early DN were randomly divided into two groups,experiment group( irbesartan plus calcium dobesilate,n =34) and control group( irbesartan,n =31 ).After 24 week treatment,the urinary albumin excretion rate(UAER),fasting blood glucose ( FBG ),postprandial blood glucose (PBG) and glycosylated hemoglobin(HbA1c) were detected and compared between two groups before and after treat ment.ResultsUAER after treatment was significantly reduced in both 2 groups(t =8.074,12.89,all P＜0.01),and the decrement in the experiment group was more obvious than that in the control group with statistical significance ( t =3.965,P ＜ 0.05).ConclusionCalcium dobesilate combined with irbesartan has good effects in the treatment of early DN.
