The prognostic value for cardiovascular events of elevated NT-proBNP in coronary heart disease patients with metabolic syndrome

VernacularTitle:氨基末端脑钠肽前体水平对冠心病合并代谢综合征患者远期心血管事件的预测意义
Author: Qun CHEN ; Changming WU ; Jianping JIANG ; Yuguo YUE
Publication Type:Journal Article
Keywords: Coronary heart disease; Metabolic syndrome; NT-proBNP; Cardiovascular events
From: Chinese Journal of Primary Medicine and Pharmacy 2012;19(15):2244-2245
CountryChina
Language:Chinese
Abstract: Objective To explore the prognostic value for cardiovascular events of elevated NT-proBNP in coronary heart disease(CHD) patients with metabolic syndrome(MS).Methods The level of NT-proBNP was measured in 165 CHD patients with MS diagnosed by coronary angiography.After 2 years follow-up,we recorded the corresponding cardiovascular events in those patients.Results The NT-proBNP level was much higher in ACS group than that in SCHD group( P ＜ 0.01 ).There were totally 45 events after 2 years.After adjustment of traditional risk factors including hypertension,diabetes,smoking history and high sensitivity C reactive protein( hs-CRP),Cox proportional hazard analysis indicated that high NT-proBNP level( ＞ 111.58ng/L)was an independent risk factor for future events (relative risk 2.67,P ＜0.01 ).Conclusion Elevated NT-proBNP level might be one of the independent risk factor for cardiovascular events in CHD patiens with MS.