Clinical effect of xipayiguyinye on oral bacteria in vitro and gingivitis in vivo
10.3760/cma.j.issn.1008-6706.2012.15.012
- VernacularTitle:西帕依固龈液体外抑制牙周可疑致病菌的临床疗效
- Author:
Mingfang SHU
;
Minghui YANG
;
Gangling YANG
- Publication Type:Journal Article
- Keywords:
Xipayiguyinye;
Gingivitis;
Bacteriostasis
- From:
Chinese Journal of Primary Medicine and Pharmacy
2012;19(15):2264-2265
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the clinical effect of Xipayinguyinye on oral bacteria in vitro and gingivitis in vivo.Methods Took the method of agar dilution to measure the minimum inhibitory concentration (MIC) of Xipayinguyinye on Porphyromonas gingivalis ( P.gingivalis),Prevotella intermedia ( P.intermedia ) and Fusobacterium nucleatum( F.nucleatum)in vitro;choose 112 patients with simple gingivitis and they were randomly divided into the research group and control group.The research group(56 cases)received the treatment of Xipayiguyinye,while the control group(56 cases)received the treatment without effect components.Both groups received 7 days of treatment and then observed the changes of sulcus bleeding index ( SBI ) and plaque index ( PLI ) before and after the treatment.Results MICof Xipayiguyinye in vitro was 1.0g/L for P.gingivalis and F.nucleatum and 0.5g/L for P.intermedia.There was no statistifically significant difference in SBI and PLI between two groups before the treatment(P ＞0.05) ;there was significant difference in SBI and PLI of research group before and after the treatment ( P ＜ 0.05 ) ; there was no significant difference in SBI and PLI of control group before and after the treatment( P ＞ 0.05 ) ;there was significant difference in SBI and PLI in SBI and PLI between two groups after the treatment ( P ＜ 0.05 ).Conclusion Xipayiguyinye could prevent bacteriostasis well and decrease the accumulation of dental plaque,reduce SBI and improve the health of the gingiva in vivo.
