The effect of hemoperfusion combined with daytime high capacity hemofiltration in the treatment of severe acute pancreatitis
10.3760/cma.j.issn.1008-6706.2012.14.009
- VernacularTitle:血液灌流联合日间高容量血液滤过在重症急性胰腺炎治疗中的作用
- Author:
Xinghua ZHU
;
Shaoqing XUE
;
Chunli DU
- Publication Type:Journal Article
- Keywords:
Blood;
Perfusion;
Hemofiltration;
Pancreatitis
- From:
Chinese Journal of Primary Medicine and Pharmacy
2012;19(14):2098-2099
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the therapeutic value of hemoperfusion combined with daytime high capacity hemofiltration in the treatment of severe acute pancreatitis.Methods The clinical data of 25 patients with severe acute pancreatitis treated by hemoperfusion combined with daytime high capacity hemofiltration(the observation group) were retrospectively analyzed,and compared with 30 severe acute pancreatitis patients without blood purification treatment(the control group).Results After the treatment,the biochemical indicator of the observation group was improved obviously compared with pre-treatment.Of the observation group,the hospital slaying time was shorter [(21.6±12.3) d vs(30.8±15.6) d],and the cure rate was higher(72％ vs 40％),and the death rate was lower (16％ vs 30％),compared with the control group(all P ＜ 0.05),but the treatment costs had no difference between the two groups.Conclusion Patients with severe acute pancreatitis on the basis of conventional treatment should conduct as early as possible hemoperfusion combined with daytime high capacity hemofiltration,and it could improve the success rate of the rescue and shorthen the length of hospital stay,and its curative effect was accurate.
