Diagnostic value of the levels of white cell count and C-reactive protein for paediatric appendicitis
10.3760/cma.j.issn.1008-6706.2012.14.013
- VernacularTitle:白细胞计数及C-反应蛋白水平对儿童阑尾炎的诊断价值
- Author:
Xianglong WANG
- Publication Type:Journal Article
- Keywords:
Appendicitis;
Leukocyte count;
C-reactive protein;
Child
- From:
Chinese Journal of Primary Medicine and Pharmacy
2012;19(14):2106-2107
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the accuracy of white cell count(WCC) and C-reactive protein(CRP) for diagnosing severity of acute paediatric appendicitis.Methods Clinicopathologic characters,WCC,CRP,histology were analyzed in 150 children undergoing open appendectomy for acute appendicitis.Results Appendix was grossly inflamed in 123 of which 24 had perforation.Histology revealed simple acute appendicitis in 99(66.0％),gungnenous appendicitis in 24(16.0％) and the rest were normal.The duration of symptoms(4.6±5.6) time,temperature (38.3±0.9)℃,WCC[(15.6±4.7) × 109/L]and CRP[(1610±653)mg/L]were significantly worse in the perforated group(P ＜ 0.01).WCC had a higher accuracy and sensitivity than CRP in diagnosing simple acute appendicitis.The combined sensitivities of WCC and CRP were 93％ and 99％ for diagnosing simple acute appendicitis and a perforated appendix,respectively.Conclusion Accuracy of WCC was higher than CRP for diagnosing simple acute appendicitis.The combined sensitivity of WCC and CRP increases for simple acute appendicitis as well as perforated appendix.
