Comparison of the influence of sevoflurane and propofol on cardiac damage of surgery patients with hypertension

VernacularTitle:七氟烷与丙泊酚麻醉对老年高血压患者围手术期心肌损伤的影响比较
Author: Yulian QU ; Qingquan HE ; Hongxia CHEN
Publication Type:Journal Article
Keywords: Sevoflurane; Propofol; Cardiac damage
From: Chinese Journal of Primary Medicine and Pharmacy 2012;19(14):2124-2125
CountryChina
Language:Chinese
Abstract: Objective To compare the effect of sevoflurane and propofol in elderly surgery patients towards cardiac damage.Methods 45 elderly patients with hypertension were divided into Sevoflurane group and Propofol group,which were observed changes of their ECG ST-segment,Mb,CK-MB,cTnI.Results 24 hours after induction of anesthesia,cardiac damage could be observed;Compared with Sevoflurane group,levels of CK-MB,Mb and cTnI increased significantly 24 hours after induction of anesthesia(t =2.771,0.681,0.557,all P ＜ 0.05),ST-segment significantly depressed at the same time[(-1.96±0.06)mV,(-1.45±0.04)mV](P ＜0.05).Conclusion Elderly patients with hypertension show cardiac damage during pevi-operative stage;Compared with propofol,sevoflurane shows lighter damage to cardiac muscle.