Clinical effect of paclitaxel and cisplatin concurrent radiotherapy and chemotherapy for advanced cervical cancer

VernacularTitle:紫杉醇联合顺铂同步放化疗治疗中晚期宫颈癌
Author: Yanyan WANG ; Xiantao LI
Publication Type:Journal Article
Keywords: Paclitaxel; Cisplatin; Cervical neoplasms; Radiotherapy
From: Chinese Journal of Primary Medicine and Pharmacy 2012;19(15):2254-2255
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical efficacy of simultaneous release of paclitaxel and cisplatin chemotherapy in treatment advanced cervical cancer.Methods 90 patients with advanced cervical cancer were randomly divided into control and experimental group,the experimental group was treated with paclitaxel and cisplatin concurrent radiotherapy and chemotherapy treatment,the control group was treated with 5-Fu,bleomycin and cisplatin for treatment.Results The clinical effective rate was 84.5％,which was higher than that of the control group (65.0％) ( P ＜ 0.05 ) ; experimental group of patients whose bone marrow suppression and gastrointestinal disorders as well as opportunities arise severity were higher( P ＜ 0.05 ) ; two groups of patients the clinical side effects appear no significant differences in case-times( P ＞ 0.05 ).Conclusion The use of paclitaxel in advanced cervical cancer and cisplatin in patients with concurrent radiotherapy and chemotherapy treatment,which could effectively improve patient outcomes,improve patient survival.