The significance of the soluble Apo-1/Fas in serum and pleural effusion in differentiating tuberculous and malignant pleural effusion
10.3760/cma.j.issn.1008-6706.2012.15.015
- VernacularTitle:可溶性Apo-1/Fas对结核性和恶性胸腔积液的鉴别诊断价值
- Author:
Chunhua XU
;
Like YU
- Publication Type:Journal Article
- Keywords:
SApo-1/Fas;
Malignant/tuberculosis;
Pleural effusion
- From:
Chinese Journal of Primary Medicine and Pharmacy
2012;19(15):2270-2272
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the significance of the soluble Apo-1/Fas(sApo-1/Fas) in differentiating tuberculous and malignant pleural effusion.Methods The level of sApo-1/Fas was detected by enzyme linked immunosorbent assay(ELISA).in serum and pleural effusion of 50 cases with malignant pleural effusion and 48 cases with tuberculous pleural effusion.Results The level of sApo-1/Fas in the serum and pleural effusion of malignant pleural effusion patients were ( 16.3 ± 2.5 ) μg/L and ( 38.6 ± 13.5) μg/L,significantly higher than those of tuberculous patients with pleural effusion( all P ＜ 0.05 ).The difference of rates of serum and pleural effusion in malignant pleural effusion and tuberculous pleural effusion patients was significant( P ＜ 0.05 ).The sensitivity,specificity and accuracy of sApo-1/Fas in serum and malignant pleural effusion were 66.0％ and 93.8％ and 79.6％.Conclusion The detecting of sApo-1/Fas may play some role in differentiating tuberculous and malignant pleural effusion.
