The influence of atorvastatin on the carotid atherosclerotic plaque and prognosis of older apoplexy
10.3760/cma.j.issn.1008-6706.2012.12.003
- VernacularTitle:阿托伐他汀对老年脑卒中患者颈动脉粥样硬化斑块及预后的影响
- Author:
Wei LIU
;
Jinwen CHEN
;
Huajun LI
;
Wenjin DU
;
Dawei CHEN
;
Yanbin JIN
- Publication Type:Journal Article
- Keywords:
Brain infarction;
Carotid artery diseases;
Atorvastatin;
Prognosis
- From:
Chinese Journal of Primary Medicine and Pharmacy
2012;19(12):1765-1766
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the influence of atorvastatin on the carotid atherosclerotic plaque and prognosis of older apoplexy.Methods 124 patients with carotid atherosclerotic plaque were randomly divided into 2groups,64 cases in the observetion group who had given atorvastatin(20mg) and general,and 60 cases in control group who had given genenal treatment.The relapse rate of apoplexy,the level of blood-fat and live viability condition were compared.Results ( 1 ) In the treatment group,the recurrence rate was 4.7％,and 18.3 ％ in the control group,the difference was statistically significant(x2=5.76,P ＜ 0.05 ).The two groups of adverse events had no significant difference ( x2=0.00,P ＞ 0.05 ).(2) In the treatment group,after treatment compared with before treatment,after the treatment group compared with the control group after treatment,TC,TG,LDL-C,HDL-C levels were statistically different ( all P ＜ 0.05 ).(3) The life skills of the treatment group after treatment was signiflcantly better than the control group,the difference was statistically significant( x2 =24.18,P ＜ 0.05 ).Conclusion A torvastatin could significantly reduce the level of blood fat,improve prognosis,and reduce the rate of apoplexy,and had good effect.
