Study on the consequence of 47 patients with hepatitis B stopping adefovir dipivoxil without doctor's advice
10.3760/cma.j.issn.1008-6706.2012.12.008
- VernacularTitle:阿德福韦酯不规范停药47例临床观察
- Author:
Genling YANG
- Publication Type:Journal Article
- Keywords:
Hepatitis B;
chronic;
Adefovir;
Treatment refusal
- From:
Chinese Journal of Primary Medicine and Pharmacy
2012;19(12):1775-1776
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the damage of stopping Adefovir without doctor's advice.Methods Clinical manifestations,prognosis of 47 cases with hepatitis B stop Adefovir without doctor's advice were analyzed retrospectively.Results Among the cases stopping adefovir without doctor's advice to take a change for the worse,8 cases HBVDNA positive within a month,34 cases in 3 months,41 cases in 6 months.And 4 patients with liver cirrhosis died,33 cases took Adefovir again,10 cases took entecavir,and gradually got well.Conclusion Stopping Adefovir dipivoxil without doctor's advice may be lead to elevated HBVDNA,change for the worse.
