Plant extract anti-cancer research progress
10.3760/cma.j.issn.1673-422X.2012.08.006
- VernacularTitle:植物提取物抗肿瘤研究进展
- Author:
Jianbin ZHANG
;
Chen CHEN
;
Zezhang TAO
- Publication Type:Journal Article
- Keywords:
Plant extracts;
Antineoplastic agents,phytogenic;
Apoptosis
- From:
Journal of International Oncology
2012;39(8):579-584
- CountryChina
- Language:Chinese
-
Abstract:
Plant extracts are kinds of important anticancer drugs.Anticancer drugs research has focused on several important plant extracts such as resveratrol,ricin,epigallocatechin-3-gallate,oridonin,juglone,quercetin,matrine,nordihydroguaiaretic acid.In vitro and in vivo studies have shown that their antitumor mechanisms including induction of apoptosis,cytotoxicity,induced redifferentiation,antiangiogesis,antiinvasion and anti-metastasis.Plant extracts have multi-link and multi-target.Part of them have been used in preclinical studies.In-depth study of the anti-tumor mechanisms of plant extracts on cancer treatment is important,and the full mechanism needs further study.
