The efficacy comparison of methotrexate combined with mifepristone and laparoscopic surgery for treating ectopic pregnancy

VernacularTitle:甲氨蝶呤联合米非司酮保守治疗与腹腔镜手术治疗异位妊娠的疗效比较
Author: Qiuli JIANG ; Gang CHEN
Publication Type:Journal Article
Keywords: Pregnancy ectopic; Methotrexate; Mifepristone; Laparoscopy
From: Chinese Journal of Primary Medicine and Pharmacy 2012;19(12):1781-1782
CountryChina
Language:Chinese
Abstract: Objective To investigate the efficacy of metholrexate combined with rmifepristone and laparoscopic surgery for treating ectopic pregnancy.Methods 85 patient with ectopic pregnancy were selected.41 cases treated with methotrexate and mifeprisione were considered as the control group,while 44 cases with laparoscopic surgery were considered as the observalion group on the voluntary basis.The clinical efficacy,serum β-HCG value and recovery time after 7d were compared between the two groups.Results After the treatment,the cure rate in the observation group was 100％ which was significantly higher than 90％ of the control group ( P ＜ 0.05 ),the serum β-HCG value of the observation group was lower and the restoration normal time was shorter than the control group ( P ＜0.05).Conclusions Laparoscopic surgery and conservative treatment of methotrexate combined with mifepristone are effective in the treatment of ectopic pregnancy.However,the clinical efficacy of the laparoscopic surgery is better and it has rapid recovery time,and it can completely cure the patients.