Postoperative radiotherapy and chemotherapy in cervical cancer
10.3760/cma.j.issn.1673-422X.2012.08.018
- VernacularTitle:宫颈癌的术后放化疗
- Author:
Yi XIA
;
Yunhai LI
;
Sen ZHAO
- Publication Type:Journal Article
- Keywords:
Uterine cervical neoplasms;
Radiotherapy;
Drug therapy
- From:
Journal of International Oncology
2012;39(8):622-625
- CountryChina
- Language:Chinese
-
Abstract:
Local recurrence is more frequent in postoperative cervical cancer patients with high-risk factors.It is confirmed that adjuvant pelvic radiotherapy (RT) for the cervical cancer patients after surgery with high-risk factors can improve local control but can't improve the overall survival.Researches show that concurrent chemo-radiotherapy (CCRT) can improve survival rates compared with radiotherapy,but the adverse effects such as leucopenia and gastrointestinal toxicity are observed frequently.Intensity-modulated radiation therapy (IMRT) has been developed to deliver a high radiation dose to an irregular target volume,with relative sparing of adjacent normal tissues.IMRT has excellent local tumor control and overall survival.
