Dickkopf-1 and bone metastases
10.3760/cma.j.issn.1673-422X.2012.08.019
- VernacularTitle:Dickkopf-1与骨转移癌
- Author:
Hua QIAO
;
Lina YOU
;
Guhong FAN
- Publication Type:Journal Article
- Keywords:
Gene expression regulation;
Neoplasm metastasis;
Neoplasms,bone tissue
- From:
Journal of International Oncology
2012;39(8):626-628
- CountryChina
- Language:Chinese
-
Abstract:
Recent studies show that the abnormalities of dickkopf-1 (DKK-1)are closely related to the bone metastasis and therapeutic effect of breast cancer,prostatic carcinoma,multiple myeloma,neuroblastoma and non-small cell lung cancer.Clinical researches of large sample on the relationships between serum DKK-1 concentration and malignant tumors bone metastases have important clinical significance for evaluating the value of DKK-1 as a clinical biological biomarker of bone metastases and understanding the tumor mechanisms of bone metastases.
