Antineoplastic agents-induced pulmonary toxicity
10.3760/cma.j.issn.1673-422X.2012.08.007
- VernacularTitle:常用抗肿瘤药物相关肺毒性
- Author:
Linghui DENG
;
Min TAO
- Publication Type:Journal Article
- Keywords:
Drug toxicity;
Antineoplastic agents;
Lung diseases,interstitial;
Lung
- From:
Journal of International Oncology
2012;39(8):584-587
- CountryChina
- Language:Chinese
-
Abstract:
Antineoplastic agents-induced pulmonary toxicity is one of important reasons causing respiratory failure,which clinical manifestations are pulmonary inflammation,allergic reaction,vascular permeability reaction and pulmonary vascular disease.All of these may be caused by drug toxicity,immune response and increased capillary permeability and so on.Because of the nonspecific performance,it is important to exclude the other lung diseases.Once the diagnosis is clear,the antineoplastic gents should be immediately stopped and the patients should be timely administered high-dose eorticosteroid therapy.How to reduce the pulmonary toxicity induced by antineoplastic agents is becoming one of the future focuses about antineoplastic agents research.
