Clinical study on the effects of Buyang-Huanwu decoction combined with western medicine on early renal injury of patients with type 2 diabetes
10.3760/cma.j.issn.1673-4246.2012.08.004
- VernacularTitle:补阳还五汤联合胰岛素用于2型糖尿病早期肾损伤的临床研究
- Author:
Ke JIANG
;
Runzhou ZHANG
;
Wei FENG
- Publication Type:Journal Article
- Keywords:
Type 2 diabetes;
Early renal damage;
Buyang-Huanwu decoction;
insulin
- From:
International Journal of Traditional Chinese Medicine
2012;34(8):683-685
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of Buyang-Huanwu decoction combined with western medicine on early diabetic renal injury.Methods 200 cases of early diabetic renal injury were randomly recruited into study group and control group,with 100 cases in each group.The control group was treated with insulin injection and oral benazepril hydrochloride,and the blood pressure,blood lipid changes were closely monitored; while the study group was additionally treated with Buyang-Huanwu decoction on the basis of the control group.Results The total therapeutic effects in the study group was significantly higher than the control group (x2=15.62,P＜0.01).The values of FBG,2 h PG,DBP,SBP,HbAlc in both groups were significantly reduced after the treatment (P＜0.05,t=4.23,4.47,3.59,3.87,3.99 in the study group,t=4.34,4.76,4.05,3.78,3.69 in the control group) ; but the difference between the two groups had no significance (P＞0.05).Before treatment rnALB,Urea,Cr,TG and TC were not significantly different (P＞0.05) ; the values of mALB,Ureaand Cr were significantly reduced in the study group after the treatment (P＜0.05,t=4.56,3.73,3.28);especially mALB in the study group was obviously lower than the control group (P＜0.05,t=5.01).Conclusion Buyang-Huanwu decoction combined with western medicine was effective to treat early renal damage of type 2 diabetes,with the functions of reducing urinary protein,improving microcirculation and protecting renal function.
