Correlation factors of cervical lymphatic metastasis in thoracic esophageal squamous cell carcinoma
10.3760/cma.j.issn.1008-6315.2012.09.030
- VernacularTitle:胸段食管鳞癌颈部淋巴结转移相关因素分析
- Author:
Liangyun MA
;
Zefei LIAO
;
Gengjie WANG
;
Le ZHANG
;
Yijing LAI
- Publication Type:Journal Article
- Keywords:
Esophageal neoplasmas;
Lymph node metastasis;
Lymph node dissection
- From:
Clinical Medicine of China
2012;28(9):982-985
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the correlation factors of cervical lymphatic metastasis in thoracic esophageal squamous cell carcinoma.Methods Data of 62 patients with thoracic esophageal squamous cell carcinoma were retrospectively analyzed.Factors associated with cervical lymphatic metastasis were analyzed by using x2 test and multivariate Logistic regression analysis.ResultsLymphatic metastasis was found in 36 cases (58.1％ ),of which metastasis in cervical lymph node was found in 15 cases(24.2％ ).A total of 1954 lymph nodes were excised,with an average of 31.5 per patient.Of all the lymph nodes,metastasis was found in 187 (9.6％) nodes.Logistic regression showed that tumor location,tumor length,thoracic lymphatic metastasis,the metastasis number of thoracic lymph nodes and thoracic lymphatic metastasis along recurrent laryngeal nerve were independent risk factors of cervical lymphatic metastasis [ OR:1.976 ( 1.436-2.538 ),P =0.035 ; 1.346(1.032-1.683),P =0.041;3.012( 1.572-6.825),P =0.012;2.023( 1.463-4.745),P =0.025 and2.254 ( 1.483-4.952 ),P =0.020,respectively ].Conclusion The independent risk factors of cervical lymphatic metastasis are foundation of selective 3-field lymph node dissection and their validities should be validated in further clinical trials.
