Study on the related substances of Potassium dehydroandrograpolide succinate for injection
10.3760/cma.j.issn.1673-4246.2012.08.010
- VernacularTitle:注射用穿琥宁的相关物质研究
- Author:
Yujiang ZHAO
;
Jiping WANG
;
Xing JIN
;
Ling YANG
;
Wei FU
;
Xiuhong WU
- Publication Type:Journal Article
- Keywords:
Potassium dehydroandrograpolide succinate for injection;
Related substances
- From:
International Journal of Traditional Chinese Medicine
2012;34(8):703-705
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the influence factors on the quality of Potassium dehydroandrograpolide succinate for injection,and to optimize its production process.Methods The related substances were taken as the estimated standards and the orthogonal experimental method for determining the best production process was adopted.Results The water temperature and pH value had a significant effect on the related substances.The best production process was:dispensing water temperature at 40℃,pH at 6.4 and filling time being 2 h.Conclusion The optimized production process was quality control and reasonable,which can be used in industrial production.
