Value of three-dimensional color power angiography in the differential diagnosis of benign and malignant breast tumors
10.3760/cma.j.issn.1004-4477.2012.08.019
- VernacularTitle:三维彩色血管能量成像鉴别乳腺肿瘤良恶性的应用价值
- Author:
Nan ZHOU
;
Hai ZHANG
;
Feng SUN
;
Qihui PENG
;
Shilong LIU
;
Saihui MOU
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Breast neoplasms;
Diagnosis,differential;
Three-dimensional color power angiography
- From:
Chinese Journal of Ultrasonography
2012;21(8):698-700
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of three-dimensional color power angiography(3D-CPA) in the differential diagnosis of benign and malignant breast tumors.Methods 3D-CPA vascular parameters were collected and analyzed in 121 breast solid lesions (63 malignant,58 benign) in the 114 female patients.The diagnostic performances of each parameter were compared by receiver operating characteristic (ROC)cure.Results The parameters of intra-tumor flow index (FI1),flow index of shells with outside thickness of 3mm surrounding the breast tumors(FI2 ) and the ratio of FI2 and FI1 (G2) in malignant group were significantly higher than those in benign group( P ＜0.05,respectively).Analysis of the areas under ROC curve showed that the areas under FI2 curve was the largest.No significant difference( P ＞0.05) was found between the area under FI2 curve and the area under G2 curve.Comparing the area under FI2 curve to that under FI1,there was significant differences ( P ＜ 0.05).Taking FI2 ≥ 27.385 as the critical value,the sensitivity and specificity for the diagnosis of malignant breast tumors were 88.9％ and 81.0％,and the positive and negative predictive values were 83.6％ and 87.0％ respectively.Conclusions The sensitivity and specificity of 3D-CPA parameter FI2 in the diagnosis of malignant breast tumors were higher than others,FI2 with the optimal critical value of ≥27.385 could help to identify malignant from benign breast tumors.
