Vera polycythemia incorporated with hemolysis: a case report and literature review
10.3760/cma.j.issn.0254-9026.2012.08.018
- VernacularTitle:真性红细胞增多症合并溶血一例并文献复习
- Author:
Jiabin ZHU
;
Litao ZHOU
;
Lijuan ZHANG
;
Liang YU
- Publication Type:Journal Article
- Keywords:
Polycythemia vera;
Hemolysis
- From:
Chinese Journal of Geriatrics
2012;31(8):701-702
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the clinical data and laboratory features of vera polycythemia incorporated with hemolysis in one case. Methods The treatment and diagnosis of series of laboratory detection with conventional cytogenetics,mutation detection in JAK2V617F,BCR/ABL fusion gene were investigated with literature. Results JAK2V617F point mutation was detected positively,BCR/ABL fusion gene was negative and trisomic chromosome 8. The case was mend and discharged after successively treated with conventional treatment of dexamethasone,antiinfective,hepatoprotective and follow-up treatment of bloodletting,hydroxyurea and interferon.Conclusions The onset of vera polycythemia is latent which is difficult to find in the early phase.Allele-specific PCR (AS-PCR) of JAK2V617F mutation will be helpful to the diagnosis.
