The clinical analysis of dry eye in patients with primary Sj(o)gren's syndrome
10.3760/cma.j.issn.1007-7480.2012.08.005
- VernacularTitle:干燥综合征患者干眼病的临床分析
- Author:
Yuming ZHANG
;
Fangfang WANG
;
Baozhen LI
;
Yan HE
;
Yanyi PENG
- Publication Type:Journal Article
- Keywords:
Sj(o)gren's syndrome;
Dry eye;
Retrospective studies
- From:
Chinese Journal of Rheumatology
2012;16(8):523-526
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical characteristics of primary Sj(o)gren's syndrome (pSS) patients with dry eyes.Methods Ninety-six pSS patients with dry eyes admitted to the Department of Rheumatology and Immunology,the Affiliated Hospital of Guilin Medical College from August 2009 to August 2011 were retrospectively analyzed.Results In all 96 patients,89 patients had symptoms,23 of whom had two or more symptoms.The tear-film break-up time (BUT) of 154 eyes were Less than 5 seconds,18 were between 5-10 second,and twenty were more than 10 seconds,with the average of 3.7±1.9 seconds.The length of tear flow of 154 eyes'width of tear mocus was less than 3 millimetres (mm),with the average of (0.21±0.10) mm.The average score of corneal fluorescein staining score was 5.2±2.4.The wet lengths of filter paper of 192 eyes were all less than 10 mm/5 min,with the average of (4.6±1.8) mm.The average score of meibomian gland function was 1.5±0.9.Conclusion In patients with pSS,the width of tear meniscus and the wet lengths of filter paper are reduced,which implies less tear secretion.At the same time,BUTs are short,and the Meibomian gland dysfunction are observed.Dry eyes of pSS are mixed in type,not only aqueous tear deficiency.
