Analysis of high risk factors and classification for biliary tract complication following liver transplantation
10.3760/cma.j.issn.1007-8118.2012.08.011
- VernacularTitle:肝移植术后胆道并发症的Clavien分级及高危因素分析
- Author:
Dejun YANG
;
Haibin ZHANG
;
Nan ZHU
;
Wei CHEN
;
Xiqiang WANG
;
Guangshun YANG
- Publication Type:Journal Article
- Keywords:
Liver transplantation;
Biliary complication;
High risk factors;
Clavien classification
- From:
Chinese Journal of Hepatobiliary Surgery
2012;18(8):611-614
- CountryChina
- Language:Chinese
-
Abstract:
Objective To retrospectively study the high risk factors for biliary complication (BC) and the application of the Clavien system to classify BC in a large cohorts of subjects undergoing liver transplantations (LT).Methods The clinical data of 181 patients who received LT from Jan.2004 to Dec.2008 were studied.BC was classified using the Clavien system.The risk factors of biliary complication were evaluated by using a binary forward stepwise logistic regression analysis.Results 14.4％ (26/181) recipients developed BC (BC group).In 84.6％ (22/26) patients the BC was above the Clavien Ⅲ b.Regression analysis of BC revealed that the placement of a T tube (P =0.0090,OR=31.177),RIld (P=0.0094,OR＜0.001).RI1w (P=0.0013,OR＞999.999) were significantly associated with the development of BC.Regression analysis of BC above Clavien Ⅲ b revealed that RIld (P=0.0065,OR＜0.001,RI1w (P=0.0022,OR＞999.999) were significantly associated with the development of BC above Clavien Ⅲ b.Conclusions The Clavien classification system was useful to classify BC.The placement of a T tube was an independent risk factor to predict BC,it was not a factor for BC above Clavien Ⅲ b.Hepatic arterial insufficiency (HAI) was an independent risk factor for BC and BC above Clavien Ⅲ b.
