Decreased regional homogeneity in patients with poststroke depression:a resting-state functional magnetic resonance imaging study
10.3760/cma.j.issn.1673-4165.2012.07.003
- VernacularTitle:卒中后抑郁患者的局部一致性降低:静息态功能磁共振成像研究
- Author:
Zufu ZHU
;
Dongbai LIU
;
Jianyu ZHANG
;
Dinghua LIU
;
Xianping MENG
;
Shiming CAI
- Publication Type:Journal Article
- Keywords:
Stroke;
Depression;
Magnetic Resonance Imaging
- From:
International Journal of Cerebrovascular Diseases
2012;20(7):501-503
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the characteristics of resting-state functional magnetic resonance imaging (fMRI)in patients post-stroke depression (PSD).Methods Resting-state fMRI scans were performed in 13 patients with and without post-stroke depression.A regional homogeneity (ReHo) approach was used as an indicator.The brain function was analyzed in patients with post-stroke depression.Results Compared to a control group,the ReHo values decreased significantly in a PSD group in the left middle frontal gyrus,right superior frontal gyrus,right middle frontal gyrus,right anterior cingulate gyrus,right posterior cingutate gyrus,left insular lobe,left caudate nucleus,and left hippocampus.Conclusions The patients with PSD had restingstate neural circuit dysfunction,suggesting that the need to focus on the emotional state of stroke patients in the clinical treatment process.
