Therapeutic strategies for dealing with cutaneous emphysema of chest wall and/or pneumomediastinum caused by severe triphosgene poisoning
10.3760/cma.j.issn.1671-0282.2012.07.014
- VernacularTitle:急性光气中毒致皮下和/或纵隔气肿的治疗
- Author:
Linlin ZHANG
;
Shusheng ZHOU
;
Zimin SUN
;
Tianjun YANG
;
Shoujun ZHU
;
Hua FAN
;
Bao LIU
- Publication Type:Journal Article
- Keywords:
Triphosgene;
Cutaneousemphysema of chest wall and (or) pneumomediastinum;
Therapy
- From:
Chinese Journal of Emergency Medicine
2012;21(7):732-735
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the clinical features and the effect of therapy on cutaneous emphysema of chest wall and/or pneumomediastinum complicated in severe acute triphosgene poisoning patients.Methods Among 81 triphosgene poisoning patients,5 complicated with cutaneousemphysema of chest wall and/or pneumomediastinum were analyzed in respect of the clinical data including age,gender,arterial blood gas (ABG),modes of mechanical ventilation support and so on.Results Five patients consisting of 3 males and 2 females,aged (23.20 ± 5.17) years,were complicated with cutaneous emphysema of chest wall and/or pneumomediastium with a prevalence rate of 0.06％.Of them,4 were alleviated completely and 1 died of acute respiratory distress syndrome (ARDS).There was no significant difference in arterial blood gas analysis (ABG) between patients with cutaneousemphysema and/or pneumomediastinum and patients without ( P ＞ 0.05 ).Conclusions Triphosgene-induced acute lung injury treated with mechanical ventilation support with high PEEP is highly suggested as high risk factor for the formation of cutaneous emphysema of chest wall and/or pneumomediastinum in severe acute Triphosgene poisoning patients.It is very important to set the PEEP level of mechanical ventilation support as low as possible for avoidance of alveolar rupture.
